A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia

Non-obstructive azoospermia (NOA) is one of the most severe forms of male infertility. Its pathophysiology is largely unknown, and few genetic influences have been defined. To identify common variants contributing to NOA in Han Chinese men, we performed a three-stage genome-wide association study of 2,927 individuals with NOA and 5,734 controls. The combined analyses identified significant (P < 5.0 × 10(-8)) associations between NOA risk and common variants near PRMT6 (rs12097821 at 1p13.3: odds ratio (OR) = 1.25, P = 5.7 × 10(-10)), PEX10 (rs2477686 at 1p36.32: OR = 1.39, P = 5.7 × 10(-12)) and SOX5 (rs10842262 at 12p12.1: OR = 1.23, P = 2.3 × 10(-9)). These findings implicate genetic variants at 1p13.3, 1p36.32 and 12p12.1 in the etiology of NOA in Han Chinese men.     

Solidification microstructure and phase constitution of Fe-7.5%Mo-16.5%Si ternary quasiperitectic alloy

Solidification of Fe-7.5%Mo-16.5%Si ternary quasiperitectic alloy is investigated by using differential scanning calorimetry (DSC) and drop tube containerless processing techniques.The primary phase is identified as R (Fe5Mo3Si2) and the quasiperitectic phases are τ1 (Fe5MoSi4) and Fe3Si.With the decrease of droplet diameter, the cooling rate and undercooling of the droplets in-crease rapidly.The experiment result indicates that the solidification microstructure is composed of remnant primary phase, qua-sip...     

人工挖孔灌注桩施工及质量控制要点

从施工及监理的角度,主要从施工前的准备、挖孔、钢筋笼、浇注砼及成桩等几个方面较为详尽地阐述了人工挖孔灌注桩的施工及质量验收的要点。     

新型环氧类扩链剂合成

通过悬浮聚合的方法,将苯乙烯与甲基丙烯酸缩水甘油酯共聚,制备了一种新型的环氧类扩链剂.通过红外光谱法确定了产品的分子结构,热分析结果表明苯乙烯-甲基丙烯酸缩水甘油酯具有较好的热稳定性.环氧当量测定及粘度测定结果表明新型环氧类扩链剂应用性能与巴斯夫公司市售的环氧类扩链剂4360S以及4370S基本相同,但在经济性方面明显优于以上两种产品,表明所制备的环氧类扩链剂具有良好的市场前景及市场竞争力.     

大学英语《综合教程》的特色与教学组织模式

文章介绍并分析了新世纪大学英语系列教材之主干课程《综合教程》编写的宗旨和特色,探讨了在教学实践中如何贯彻《综合教程》的编写宗旨,彰显其特色,以取得良好的教学效果。     

Theoretical analysis of reactive solid-liquid interfacial energies

The characterization of reactive solid-liquid interfacial energies and solid surface energies is a pressing problem in materials science and surface science. Based on the concept that unbalanced forces doing work, a mathematical formulation between surface energies and interfacial energies for reactive wetting is presented. The resulting formalism has significant generality in which the equilibrium Young’s equation for solid-liquid interfacial energies is just a special case. It is shown that a solid-liquid interfacial energy at non-equilibrium is always higher than that at equilibrium, and that the transformation of reactive interfaces to equilib-rium interfaces is an inevitable, spontaneous process. The numerical range of solid-liquid interfacial energies γsl for a limited, solid-liquid interfacial wetting system was calculated to be 0 ≤γsl ≤γsg. The calculation methods for reactive solid-liquid interfacial energies and solid surface energies are presented. They are significant for composite materials and weld, powder sinter, package of electronic devices, and other surface and interfacial issues in metallurgy.     

管道输油价格模型

论述了管道输油成本与所输原油的物性，输量及管道工程技术参数间的关系，分析了市场经济体制下经济价格模型对管道输油的局限性，提出了市场经济条件下，适合我国国情的管道输出价格模型，并阐述了其操作方法。     

1996年～1997年洪湖湿地鸟类调查报告

１９９６年～１９９７年对洪湖的鸟类调察中共记录到１３０种鸟类，隶属１６目，４０科，比１９８１年～１９８２年减少２科，３７种，但有７种为首次记录，以冬候鸟为主体（冬候鸟３７％，夏候鸟２６％，留鸟２６％，旅鸟１２％）冬春季狩猎水禽数量逐渐减少，鸭属的捕获最下降至１０％，骨顶鸡（Ｆｕｌｉｃａａｔｒａ）上升到９０％，发现国家重点保护野生动物１６种：１级４种，ＩＩ级１２种。     

高维Jorgensen不等式的应用

应用高维Jorgensen不等式得到了如下定理 :设g、h∈M( Rn) ,g是严格抛物元 ,是离散群 ,g和h无公共不动点 ,那么对 x∈Hn+ 1,sinh 12 ρ(x ,gx)sinh 12 ρ(x ,hgh- 1x)≥ 14。     

关于供暖系统运行管理问题的探讨

为了保证供暖系统的正常运行，除在设计中认真进行水力计算外，不应在施工中严格按规范进行操作，按程序进行交工验收，同时运行中要加强维护管理，只有三者有机结合才能提高供热质量。